X-ray fluorescence imaging of uranium distribution in human dopaminergic cells Carmona A., Somogyi A., Roudeau S., Porcaro F., Medjoubi K., Vidaud C., Malard V., Bresson B., Ortega R. (2023) AIP Conf. Proc. 27 September; 2990 (1): 020007. https://doi.org/10.1063/5.0168512

Coupling SEC and IEF to SXRF for metallation analysis of SOD1 enzyme isolated from the human central nervous system Roudeau S., Trist B.G., Carmona A., Davies K.M., Halliday G.M., Rufin Y., Claverol S., Van Malderen S.J.M., Falkenberg G., Double K.L., Ortega R. (2023) AIP Conf. Proc. 27 September; 2990 (1): 020005. https://doi.org/10.1063/5.0168366

Correlating STED and synchrotron XRF nano-imaging to explore metal functions in synapses Domart F., Cloetens P., Roudeau S., Carmona A., Verdier E., Choquet D., Ortega R. (2023) AIP Conf. Proc. 27 September; 2990 (1): 020006. https://doi.org/10.1063/5.0168303

Multimodal and multiscale correlative elemental imaging: From whole tissues down to organelles. Roudeau S., Carmona A., Ortega R. (2023)  Current Opinion in Chemical Biology, 76, 102372.

Des métaux dans les neurones. Richard Ortega. Dans : L’Interdisciplinarité – Voyages au-delà des disciplines. S. Blanc, M. Bouzeghoub , M. Knoop, CNRS éditions, pp 187-191 (2022)

Correlative nano-imaging of metals and proteins in primary neurons by synchrotron X-ray fluorescence and STED super resolution microscopy: Experimental validationRichardOrtega, StéphaneRoudeau, AsuncionCarmona Journal of Neuroscience Methods Volume 381,1 November 2022, 109702

Altered SOD1 maturation and post-translational modification in amyotrophic lateral sclerosis spinal cord Benjamin G Trist, Sian Genoud,Stéphane Roudeau,Alexander Rookyard,Amr Abdeen,Veronica Cottam,Dominic J Hare,Melanie White,Jens Altvater,Jennifer A Fifita…Show moreBrain, awac165

Neurotoxicity of environmental metal toxicants: special issue Ortega R., Carmona A.Toxics (2022) 10(7), 382

Imaging the structural organization of chemical elements in growth cones of developing hippocampal neurons
Asuncion Carmona, Si Chen, Florelle Domart, Daniel Choquet, Richard Ortega
Metallomics (2022) 14(1), mfab073

Molecular Mechanisms of Environmental Metal Neurotoxicity: A Focus on the Interactions of Metals with Synapse Structure and Function Asuncion Carmona, Stéphane Roudeau, Richard Ortega Toxics (2021), 9(9), 198

Native Separation and Metallation Analysis of SOD1 Protein from the Human Central Nervous System: a Methodological Workflow Stéphane Roudeau, Benjamin G. Trist, Asuncion Carmona, Katherine M. Davies, Glenda M. Halliday, Yann Rufin, Stéphane Claverol, Stijn J.M. Van Malderen, Gerald Falkenberg, Kay L. Double and Richard Ortega Analytical Chemistry 2021, 93, 32, 11108–11115

Cytoplasmic aggregation of uranium in human dopaminergic cells after continuous exposure to soluble uranyl at non-cytotoxic concentrations Carmona A., Porcaro F., Somogyi A., Roudeau S., Domart F., Medjoubi K., Aubert M., Isnard H., Nonell A., Rincel A., Paredes E., Vidaud C., Malard V., Bresson C., Ortega R. (2021), NeuroToxicology, 82, 35-44.

Mass spectrometry – based imaging techniques for iodine-127 and iodine-129 detection and localization in the brown alga Laminaria digitata Lebeau D., Leroy N., Doizi D., Wu T-D, Guerquin-Kern JL, Perrin L., Ortega R., Voiseux C., Fournier JB, Potin P, Fiévet B., Leblanc C. (2021), Journal of Environmental Radioactivity, 231, 106552. 

How much manganese is safe for infants? A review of the scientific basis of intake guidelines and regulations relevant to the manganese content of infant formulas Mitchell E.J., Frisbie S.H., Roudeau S., Carmona A., Ortega R. (2020), Journal of Trace Elements in Medicine and Biology, 126710. 

Native separation and metallation analysis of SOD1 protein from the human central nervous system: A methodological workflow Roudeau S., Trist B.G., Carmona A., Davies K.M., Halliday G.M., Rufin Y., Claverol S., Van Malderen S.J.M., Falkenberg G., Double K.L., Ortega R. (2020), ChemRxiv. 

Correlating STED and synchrotron XRF nano-imaging unveils cosegregation of metals and cytoskeleton proteins in dendrites Domart F., Cloetens P., Roudeau S., Carmona A., Verdier E., Choquet D., Ortega R. (2020), eLife, 9:e62334.

Estimating daily intakes of manganese due to breast milk, infant formulas, or young child nutritional beverages in the United States and France: Comparison to sufficiency and toxicity thresholds Mitchell E.J., Frisbie S.H., Roudeau S., Carmona A., Ortega R. (2020), Journal of Trace Elements in Medicine and Biology, 62:126607. 

Manganese levels in infant formula and young child nutritional beverages in the United States and France: comparison to breast milk and regulations Frisbie S.H., Mitchell E.J., Roudeau S., Domart F., Carmona A., Ortega R. (2019), PLoS ONE, 14(11): e0223636.

Mapping chemical elements and iron oxidation states in the substantia nigra of 6-hydroxydopamine lesioned rats using correlative immunohistochemistry with proton and synchrotron micro-analysis Carmona A., Roudeau S., Perrin L., Carcenac C., Vantelon D., Savasta M., Ortega R. (2019), Frontiers in Neuroscience, 13:1014.

Manganese mapping using a fluorescent Mn2+ sensor and nanosynchrotron X-ray fluorescence reveals the role of the Golgi apparatus as a manganese storage site Das S., Carmona A., Khatua K., Porcaro F., Somogyi A., Ortega R., Datta A. (2019), Inorganic Chemistry, 58, 13724-13732.

Isotopic variations of copper at the protein fraction level in neuronal human cells exposed in vitro to uranium Paredes Paredes E., Malard V., Vidaud C., Avazeri E., Ortega R., Nonell A., Isnard H., Chartier F., Bresson C. (2019), Analyst, 144, 5928-5933.

Deciphering the uranium-target proteins in human dopaminergic SH-SY5Y cells Vidaud C., Robert M., Paredes E., Ortega R., Avazeri E., Jing L., Guigonis J.M., Bresson C., Malard V. (2019), Archives of Toxicology, 93, 2141-2154.

Emerging chemical tools and techniques for tracking biological manganese Das S., Khatua K., Rakshit A., Carmona A., Sarkar A., Bakthavatsalam S., Ortega R., Datta A. (2019), Dalton Transactions, 48, 7047-7061.

SLC30A10 mutation involved in parkinsonism results in manganese accumulation within nano-vesicles of the Golgi apparatus Carmona A., Zogzas C.E., Roudeau S., Porcaro F., Garrevoet J., Spiers K., Salome M., Cloetens P., Mukhopadhyay S., Ortega R. (2019), ACS Chemical Neuroscience, 10, 1, 599-609. [pubmed]

Uranium exposure of human dopaminergic cells results in low cytotoxicity, accumulation within sub-cytoplasmic regions, and down regulation of MAO-B Carmona A., Malard V., Avazeri E., Roudeau S., Porcaro F., Paredes E., Vidaud C., Bresson C., Ortega R. (2018), NeuroToxicology, 68, 177-188. [pubmed] 

Impact of uranium uptake on isotopic fractionation and endogenous element homeostasis in human neuron-like cells Paredes E., Avazeri E., Malard V., Vidaud C., Reiller P.E., Ortega R., Nonell A., Isnard H., Bresson C. (2018), Scientific Reports, 8, 17163.

Advances in element speciation analysis of biomedical samples using synchrotron-based techniques Porcaro F., Roudeau S., Carmona A., Ortega R. (2018), Trends in Analytical Chemistry, 104, 22-41.

A new procedure for high precision isotope ratio determinations of U, Cu and Zn at nanogram levels in cultured human cells: what are the limiting factors? Paredes E., Avazeri E., Malard V., Vidaud C., Ortega R., Nonell A., Isnard H., Chartier F., Bresson C. (2018), Talanta, 178, 894-904.